Anti-Clostridium botulinum Toxin B抗体[GR-3G7] (ab59715)

概述

  • 产品名称Anti-Clostridium botulinum Toxin B抗体[GR-3G7]
  • 描述
    小鼠单克隆抗体[GR-3G7] to Clostridium botulinum Toxin B
  • 特异性This antibody reacts with Clostridium botulinum Toxin B.
  • 经测试应用适用于: Flow Cyt, Competitive ELISAmore details
  • 种属反应性
    Reacts with Clostridium botulinum.
  • 免疫原

    Genetic immunisation with cDNA encoding Clostridium botulinum Toxin B.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号GR-3G7
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab59715 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 1.2µg for 106 cells. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
Competitive ELISA 1/200 - 1/400.

靶标

  • 相关性Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the 76 Gln | Phe 77 bond of synaptobrevin 2.
  • 细胞定位Secreted
  • 别名
    • BoNT/B antibody
    • Bontoxilysin B antibody
    • BontoxilysinB antibody
    • bot B antibody
    • botB antibody
    • Botulinum neurotoxin type B antibody
    see all

Anti-Clostridium botulinum Toxin B antibody [GR-3G7] 图像

  • BOSC23 cells were transiently trans-fected with an expression vector encoding either Clostridium botulinum Toxin B (red curve) or an irrelevant protein (control transfectant). Binding of ab59715 was detected with a PE conjugated secondary antibody. A positive signal was obtained only with Clostridium botulinum Toxin B transfected cells.

Anti-Clostridium botulinum Toxin B antibody [GR-3G7] (ab59715)参考文献

ab59715 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us with your question and for your patience while I have been in touch with the lab about ab59715. This antibody was raised against the light chain and has only been tested for reactivity with the light chain, so it most...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"