Anti-Clostridium botulinum C Toxoid抗体(ab27165)

概述

  • 产品名称Anti-Clostridium botulinum C Toxoid抗体
  • 描述
    兔多克隆抗体to Clostridium botulinum C Toxoid
  • 特异性This antibody reacts with type C toxoid in an ELISA testing against toxoids A through F. Protection for both toxin type C and D in a mouse bioassay has been observed.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    Reacts with
  • 免疫原

    Type C botulinum toxin treated with formaldehyde to avoid toxicity.

  • 常规说明


    Inhibitory activity in a mouse bioassay is specific for lethal doses of both type C and D toxin at a serum dilution of 1:100.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 15mM Sodium Azide.
    Constituents: Whole serum.
  • 纯度Whole antiserum
  • Primary antibody说明Inhibitory activity in a mouse bioassay is specific for lethal doses of both type C and D toxin at a serum dilution of 1:100.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab27165 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/8000.

In a toxoid ELISA with 1 µg toxoid/well the titre of this serum (specific absorbance values >1.5) is well above 8,000.

靶标

  • 相关性Clostridium botulinum is a large anaerobic bacteria which causes the disease botulism. Seven different toxigenic types exist, each producing an immunologically distinct form of botulinum toxin, designated A,B,C1,D,E,F and G. These are neurotoxins that bind with high affinity to the peripheral neuronal presynaptic membrane. They hydrolyze SNAP 25, thereby blocking release of the neurotransmitter acetylcholine. This results in flaccid paralysis with frequent heart or respiratory failure.
  • 细胞定位Secreted
  • 别名
    • BoNT/C1 antibody
    • Bontoxilysin C1 antibody
    • Botulinum neurotoxin C1 antibody
    • Botulinum neurotoxin type C1 nontoxic component antibody
    • Botulinum neurotoxin type C1 antibody
    • Botulism toxin C antibody
    • Clostridium botulinum toxin C antibody
    see all

Anti-Clostridium botulinum C Toxoid antibody (ab27165)参考文献

ab27165 has not yet been referenced specifically in any publications.

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