Anti-Clostridium botulinum A Toxoid抗体[B29M] (ab37344)

概述

  • 产品名称Anti-Clostridium botulinum A Toxoid抗体[B29M]
    参阅全部 Clostridium botulinum A Toxoid 一抗
  • 描述
    小鼠单克隆抗体[B29M] to Clostridium botulinum A Toxoid
  • 特异性Clostridium botulinum Type A Neurotoxin Heavy Chain.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    Reacts with Clostridium botulinum. Not yet tested in other specie.
  • 免疫原

    Synthetic peptide:

    DRVYINVVVKNKEYRLATN

    , corresponding to amino acids 1177-1195 of Clostridium botulinum A Toxoid

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度>95% by SDS-PAGE
  • 纯化说明ab37344 was purified from ascites by euglobulin precipitation.
  • 克隆单克隆
  • 克隆编号B29M
  • 同种型IgM
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab37344 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 149 kDa. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.
    • 别名
      • Atx antibody
      • BotA antibody
      • BOTOX antibody
      • Botulinum neurotoxin type A antibody
      • Botulism A toxoid antibody
      see all

    Anti-Clostridium botulinum A Toxoid antibody [B29M] (ab37344)参考文献

    This product has been referenced in:
    • Tok JB & Fischer NO Single microbead SELEX for efficient ssDNA aptamer generation against botulinum neurotoxin. Chem Commun (Camb) :1883-5 (2008). Read more (PubMed: 18401506) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. I have been in contact with the originator of this antibody, and this is the response I received: Most antibody manufacturers use an extinction coefficient of 1.35-1.4 for IgG as well as IgM. There was some theory years ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"