Anti-Clostridium botulinum A Toxoid抗体(ab27163)

概述

  • 产品名称Anti-Clostridium botulinum A Toxoid抗体
    参阅全部 Clostridium botulinum A Toxoid 一抗
  • 描述
    兔多克隆抗体to Clostridium botulinum A Toxoid
  • 特异性In an ELISA testing against toxins A through F this serum reacts primarily with A toxin but does also have some cross reactivity with B toxin. However, type protection in a mouse bioassay is monospecific for the A toxin. In a toxoid ELISA with 1ug toxoid/well the titre of this serum (specific absorbance values >1.5) is well above 16,000. Inhibitory activity in the mouse bioassay is specific for lethal doses of type A toxin at a serum dilution of 1:100.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    Reacts with
  • 免疫原

    Type A botulinum toxin treated with formaldehyde for detoxification.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 15mM Sodium Azide.
    Constituents: Whole serum.
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab27163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/16000. In a toxoid ELISA with 1µg toxoid/well the titre of this serum (specific absorbance values >1.5) is well above 16,000.

靶标

  • 相关性Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.
  • 别名
    • Atx antibody
    • BotA antibody
    • BOTOX antibody
    • Botulinum neurotoxin type A antibody
    • Botulism A toxoid antibody
    see all

Anti-Clostridium botulinum A Toxoid antibody (ab27163)参考文献

ab27163 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry.

I can confirm that the toxins are produced as binary proteins that possess a heavy chain (approximately 100 kDa) and a light chain (approximately 50 kDa). The heavy chain is a binding component that directs the tox...

Read More

Thank you for your enquiry. Please find the antibody originator's comments below: I'm very confident that this antibody will react with both the heavy and light chain of BoTox A as this is a polyclonal antibody raised by using whole toxin inactiva...

Read More

Thank you very much for your enquiry. I'm very sorry for the delay in responding to you. Thank you for your patience. There is no problems in ordering 15- 20 units at a time for ab2029, ab20592, ab22037, ab22041, as these are quite small amounts...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"