Anti-Clostridium botulinum A Toxoid抗体[230F9] (ab40786)

概述

  • 产品名称Anti-Clostridium botulinum A Toxoid抗体[230F9]
    参阅全部 Clostridium botulinum A Toxoid 一抗
  • 描述
    小鼠单克隆抗体[230F9] to Clostridium botulinum A Toxoid
  • 特异性BoTox-A (1280-1292) 100%; BoTox-A 100% Does not cross react with BoTox-B, BoTox-C, BoTox-E or BoTox-F (1272-1280)
  • 经测试应用适用于: ICC/IF, Inhibition Assaymore details
  • 免疫原

    Synthetic peptide analogue of the carboxyl terminal region of BoTox-A.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: Tissue culture supernatant
  • 纯度Tissue culture supernatant
  • 纯化说明Sterile filtered culture supernatant.
  • 克隆单克隆
  • 克隆编号230F9
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab40786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent dilution.
Inhibition Assay Use at an assay dependent dilution. Inhibits BoTox-A binding to Neuro2A cells treated with GT1b ganglioside which can be eliminated by prior incubation with synthetic peptide immunogen.

靶标

  • 相关性Clostridium botulinum neurotoxins are zinc-dependent proteases that block the release of acetylcholine from peripheral cholinergic nerve endings by targeting specific membrane proteins including synaptosomal-associated proteins (SNAP), vesicle-associated membrane proteins (VAMP), and syntaxins. Neurotoxin A is characteristically associated with human botulism and known to target and hydrolyse the 197-Gln-|-Arg-198 bond of SNAP-25.
  • 别名
    • Atx antibody
    • BotA antibody
    • BOTOX antibody
    • Botulinum neurotoxin type A antibody
    • Botulism A toxoid antibody
    see all

Anti-Clostridium botulinum A Toxoid antibody [230F9] (ab40786)参考文献

ab40786 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us.

The immunogen of antibody ab40786 is a "synthetic peptide analogue of the carboxyl terminal region of BoTox-A", http://www.uniprot.org/uniprot/P10845.

We have not tested this antibody in WB, if y...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"