概述

  • 产品名称Anti-CLIC6抗体
    参阅全部 CLIC6 一抗
  • 描述
    兔多克隆抗体to CLIC6
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within the internal sequence amino acids 435-484 (RREDGEASEP RALGQEHDIT LFVKAGYDGE SIGNCPFSQR LFMILWLKGV) of Human CLIC6 (NP_444507).

  • 阳性对照
    • Jurkat cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab105786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 75 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport.
  • 组织特异性Expressed in brain, placenta, pancreas and liver.
  • 序列相似性Belongs to the chloride channel CLIC family.
    Contains 1 GST C-terminal domain.
  • 结构域Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Cytoplasm. Cell membrane. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Chloride channel form A antibody
    • Chloride intracellular channel 6 antibody
    • Chloride intracellular channel protein 6 antibody
    • CLIC1L antibody
    • Clic6 antibody
    • CLIC6_HUMAN antibody
    • Parchorin antibody
    see all

Anti-CLIC6 antibody 图像

  • Anti-CLIC6 antibody (ab105786) at 0.5 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 75 kDa

Anti-CLIC6 antibody (ab105786)参考文献

ab105786 has not yet been referenced specifically in any publications.

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