Anti-CLECSF6抗体[MM0237- 5P20] (ab89188)


  • 产品名称Anti-CLECSF6抗体[MM0237- 5P20]
    参阅全部 CLECSF6 一抗
  • 描述
    小鼠单克隆抗体[MM0237- 5P20] to CLECSF6
  • 经测试应用适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    human recombinant CLECSF6 extracellular domain.



Our Abpromise guarantee covers the use of ab89188 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 28 kDa.
Flow Cyt 1/50 - 1/200. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • 功能May be involved in regulating immune reactivity. May play a role in modulating dendritic cells (DC) differentiation and/or maturation. May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation.
  • 组织特异性Expressed in dendritic cells, myeloid cells, B-cells and HL-60 cells (at protein level). TNF alpha, IL-1 alpha, and LPS, down-regulated expression at the surface of neutrophils (at protein level). Expressed preferentially in hematopoietic tissues. Expressed in peripheral blood leukocytes, neutrophils, moderate quantities in spleen, lymph node, and bone marrow, and at very low levels in thymus. Expressed in Ag-presenting cells (DC, monocytes, macrophages and B-cells), as well as on granulocytes. Expression was decreased in DC by signals inducing its maturation (e.g. CD40 ligand, LPS, and TNF alpha).
  • 序列相似性Contains 1 C-type lectin domain.
  • 结构域Contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C type (calcium dependent carbohydrate recognition domain) lectin superfamily member 6 antibody
    • C type lectin antibody
    • C type lectin DDB27 antibody
    • C type lectin superfamily 6 antibody
    • C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6 antibody
    • C-type lectin superfamily member 6 antibody
    • C-type lectin DDB27 antibody
    • C-type lectin domain family 4 member A antibody
    • C-type lectin domain family 4, member A antibody
    • C-type lectin domain family 4, member a2 antibody
    • C-type lectin superfamily member 6 antibody
    • CLC4A_HUMAN antibody
    • Clec4a antibody
    • Clec4a2 antibody
    • CLECSF6 antibody
    • DCIR antibody
    • Dcir1 antibody
    • DDB27 antibody
    • Dendritic cell immunoreceptor antibody
    • HDCGC13P antibody
    • Lectin like immunoreceptor antibody
    • Lectin, C-type, superfamily member 6 antibody
    • Lectin-like immunoreceptor antibody
    • LLIR antibody
    see all

Anti-CLECSF6 antibody [MM0237- 5P20] (ab89188)参考文献

ab89188 has not yet been referenced specifically in any publications.

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