概述

  • 产品名称Anti-CLEC9A抗体
    参阅全部 CLEC9A 一抗
  • 描述
    兔多克隆抗体to CLEC9A
  • 经测试应用适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 200 to the C-terminus of Human CLEC9A.

    (Peptide available as ab92420.)

  • 阳性对照
    • This antibody gave a positive signal in human spleen and kidney tissue lysates.

性能

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应用

Our Abpromise guarantee covers the use of ab79661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
Flow Cyt
  • 应用说明WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 27 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.
    • 组织特异性In peripheral blood highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes.
    • 序列相似性Contains 1 C-type lectin domain.
    • 翻译后修饰N-glycosylated.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C type lectin domain family 9, member A antibody
      • C-type lectin domain family 9 member A antibody
      • CLC9A_HUMAN antibody
      • CLEC9A antibody
      • DNGR1 antibody
      • HEEE9341 antibody
      • PRO34046 antibody
      • UNQ9341 antibody
      see all

    Anti-CLEC9A antibody 图像

    • All lanes : Anti-CLEC9A antibody (ab79661) at 1 µg/ml

      Lane 1 : Human spleen tissue lysate - total protein (ab29699)
      Lane 2 : Human kidney tissue lysate - total protein (ab30203)

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 27 kDa
      Observed band size : 33 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 17 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 3 minutes

    Anti-CLEC9A antibody (ab79661)参考文献

    This product has been referenced in:
    • Schreibelt G  et al. The C-type lectin receptor CLEC9A mediates antigen uptake and (cross-)presentation by human blood BDCA3+ myeloid dendritic cells. Blood 119:2284-92 (2012). Flow Cyt ; Human . Read more (PubMed: 22234694) »

    See 1 Publication for this product

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