Anti-CLEC4E抗体(ab66128)

概述

  • 产品名称Anti-CLEC4E抗体
    参阅全部 CLEC4E 一抗
  • 描述
    小鼠多克隆抗体to CLEC4E
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human) with tag

  • 阳性对照
    • Recombinant tagged CLEC4E.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 50% Glycerol, Whole serum
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab66128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: Use at an assay dependent dilution.
    WB: 1/1000 - 1/2500. Predicted molecular weight: 25 kDa.

    This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
    • 序列相似性Contains 1 C-type lectin domain.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C type lectin domain family 4 member E antibody
      • C type lectin superfamily member 9 antibody
      • C-type (calcium dependent carbohydrate recognition domain) lectin superfamily member 9 antibody
      • C-type lectin domain family 4 member E antibody
      • C-type lectin superfamily member 9 antibody
      • CLC4E_HUMAN antibody
      • CLEC 4E antibody
      • Clec4e antibody
      • CLECSF9 antibody
      • Macrophage inducible C type lectin antibody
      • Macrophage-inducible C-type lectin antibody
      • MINCLE antibody
      see all

    Anti-CLEC4E antibody 图像



    • Predicted band size : 25 kDa

    Anti-CLEC4E antibody (ab66128)参考文献

    ab66128 has not yet been referenced specifically in any publications.

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