概述

  • 产品名称Anti-CLEC1B抗体
    参阅全部 CLEC1B 一抗
  • 描述
    山羊多克隆抗体to CLEC1B
  • 特异性ab81983 is expected to recognize both reported isoforms (NP_001092901.1; NP_057593.3)
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    KGHKCSPCDTNWRY

    , corresponding to internal sequence amino acids 95-108 of Human CLEC1B (NP_001092901.1; NP_057593.3).

  • 阳性对照
    • Human bone marrow and human kidney lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab81983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: antibody detection limit dilution 1/1000.
    WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 27 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.
    • 组织特异性Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
    • 序列相似性Contains 1 C-type lectin domain.
    • 翻译后修饰Glycosylated.
      Phosphorylated on tyrosine residue in response to rhodocytin binding.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 1810061I13Rik antibody
      • C type lectin domain family 1 member B antibody
      • C type lectin like receptor 2 antibody
      • C-type lectin domain family 1 member B antibody
      • C-type lectin domain family 1, member B antibody
      • C-type lectin-like receptor 2 antibody
      • C-type lectin-like receptor-2 antibody
      • CLC1B_HUMAN antibody
      • CLEC 2 antibody
      • CLEC 2B antibody
      • CLEC-2 antibody
      • CLEC1B antibody
      • CLEC2 antibody
      • CLEC2B antibody
      • PRO1384 antibody
      • QDED721 antibody
      see all

    Anti-CLEC1B antibody 图像

    • Anti-CLEC1B antibody (ab81983) at 1 µg/ml + human kidney lysate (in RIPA buffer) at 35 µg
      Developed using the ECL technique

      Predicted band size : 27 kDa
      Observed band size : 30 kDa (why is the actual band size different from the predicted?)


      Exposure time : 1 hour

    Anti-CLEC1B antibody (ab81983)参考文献

    ab81983 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"