概述

  • 产品名称
  • 描述
    兔多克隆抗体to CLEC1B
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide corresponding to a region within N-terminal amino acids 1-50 (

    MQDEDGYITLNIKPRKQALSSAEPASSWWRVMALVLLISSMGLVVGLVAL

    ) of Mouse CLEC1B (NP_064369).

  • 阳性对照
    • Mouse pancreas lysate.

性能

应用

Our Abpromise guarantee covers the use of ab116278 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.
  • 组织特异性
    Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
  • 序列相似性
    Contains 1 C-type lectin domain.
  • 翻译后修饰
    Glycosylated.
    Phosphorylated on tyrosine residue in response to rhodocytin binding.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1810061I13Rik antibody
    • C type lectin domain family 1 member B antibody
    • C type lectin like receptor 2 antibody
    • C-type lectin domain family 1 member B antibody
    • C-type lectin domain family 1, member B antibody
    • C-type lectin-like receptor 2 antibody
    • C-type lectin-like receptor-2 antibody
    • CLC1B_HUMAN antibody
    • CLEC 2 antibody
    • CLEC 2B antibody
    • CLEC-2 antibody
    • CLEC1B antibody
    • CLEC2 antibody
    • CLEC2B antibody
    • PRO1384 antibody
    • QDED721 antibody
    see all

图片

  • Anti-CLEC1B antibody (ab116278) at 1 µg/ml + Mouse pancreas lysate at 10 µg

    Predicted band size : 27 kDa

实验方案

文献

ab116278 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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