概述

  • 产品名称Anti-CLEC1B抗体[17D9]
    参阅全部 CLEC1B 一抗
  • 描述
    大鼠单克隆抗体[17D9] to CLEC1B
  • 经测试应用适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Tissue/ cell preparation (Mouse): RBL-2H3 cells stably expressing HA-tagged mouse CLEC1B.

性能

应用

Our Abpromise guarantee covers the use of ab90542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 20 kDa.
Flow Cyt Use at an assay dependent concentration. ab18536-Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.
  • 组织特异性Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
  • 序列相似性Contains 1 C-type lectin domain.
  • 翻译后修饰Glycosylated.
    Phosphorylated on tyrosine residue in response to rhodocytin binding.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 1810061I13Rik antibody
    • C type lectin domain family 1 member B antibody
    • C type lectin like receptor 2 antibody
    • C-type lectin domain family 1 member B antibody
    • C-type lectin domain family 1, member B antibody
    • C-type lectin-like receptor 2 antibody
    • C-type lectin-like receptor-2 antibody
    • CLC1B_HUMAN antibody
    • CLEC 2 antibody
    • CLEC 2B antibody
    • CLEC-2 antibody
    • CLEC1B antibody
    • CLEC2 antibody
    • CLEC2B antibody
    • PRO1384 antibody
    • QDED721 antibody
    see all

Anti-CLEC1B antibody [17D9] 图像

Anti-CLEC1B antibody [17D9] (ab90542)参考文献

This product has been referenced in:
  • Kerrigan AM  et al. CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils. J Immunol 182:4150-7 (2009). Read more (PubMed: 19299712) »

See 1 Publication for this product

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