Anti-CLEC-2抗体[17D9] (ab90542)
Key features and details
- Rat monoclonal [17D9] to CLEC-2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG2b
概述
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产品名称
Anti-CLEC-2抗体[17D9]
参阅全部 CLEC-2 一抗 -
描述
大鼠单克隆抗体[17D9] to CLEC-2 -
宿主
Rat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus. This information is proprietary to Abcam and/or its suppliers.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
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纯度
Protein A/G purified -
克隆
单克隆 -
克隆编号
17D9 -
骨髓瘤
Y3/Ag1.2.3 -
同种型
IgG2b -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab90542于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 20 kDa.
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说明 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 20 kDa. |
靶标
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功能
Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. -
组织特异性
Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets. -
序列相似性
Contains 1 C-type lectin domain. -
翻译后修饰
Glycosylated.
Phosphorylated on tyrosine residue in response to rhodocytin binding. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 56760 Mouse
- SwissProt: Q9JL99 Mouse
- Unigene: 30700 Mouse
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别名
- 1810061I13Rik antibody
- C type lectin domain family 1 member B antibody
- C type lectin like receptor 2 antibody
see all
图片
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All lanes : Anti-CLEC-2 antibody [17D9] (ab90542)
Lane 1 : B3Z
Lane 2 : B3Z mCLEC-2
Predicted band size: 20 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab90542 被引用在 1 文献中.
- Kerrigan AM et al. CLEC-2 is a phagocytic activation receptor expressed on murine peripheral blood neutrophils. J Immunol 182:4150-7 (2009). PubMed: 19299712