Anti-CLCA4抗体(ab121524)

概述

  • 产品名称Anti-CLCA4抗体
    参阅全部 CLCA4 一抗
  • 描述
    兔多克隆抗体to CLCA4
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: WVGMVHFDST ATIVNKLIQI KSSDERNTLM AGLPTYPLGG TSICSGIKYA FQVIGELHSQ LDGSEVLLLT DGEDNTASSC IDEV, corresponding to amino acids 56-139 of Human CLCA4.

  • 阳性对照
    • Human duodenum.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20ºC.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituents: 60% PBS, 40% Glycerol
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab121524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May be involved in mediating calcium-activated chloride conductance.
  • 组织特异性Primarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp.
  • 序列相似性Belongs to the CLCR family.
    Contains 1 VWFA domain.
  • 翻译后修饰Processed at a monobasic residue to yield a larger N-terminal and a smaller C-terminal cleavage products of 90 to 110 and 30 to 35 kDa, respectively.
  • 细胞定位Cell membrane. Apical cell membrane. Secreted. The C-terminus 30 kDa form is anchored to the membrane (By similarity). The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 30 kDa form antibody
    • CaCC-2 antibody
    • Calcium-activated chloride channel family member 4 antibody
    • Calcium-activated chloride channel protein 2 antibody
    • Calcium-activated chloride channel regulator 4 antibody
    • Clca4 antibody
    • CLCA4_HUMAN antibody
    • hCaCC-2 antibody
    • hCLCA4 antibody
    see all

Anti-CLCA4 antibody 图像

  • ab121524, at 1/10 dilution, staining human duodenum by immunohistochemistry on paraffin embebbed tissues (IHC-P).

Anti-CLCA4 antibody (ab121524)参考文献

ab121524 has not yet been referenced specifically in any publications.

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