Anti-Clathrin heavy chain抗体[TD.1] (ab24578)


  • 产品名称Anti-Clathrin heavy chain抗体[TD.1]
    参阅全部 Clathrin heavy chain 一抗
  • 描述
    小鼠单克隆抗体[TD.1] to Clathrin heavy chain
  • 特异性This antibody reacts with clathrin heavy chains (CHC).
  • 经测试应用适用于: IHC-P, WB, ICC/IFmore details
    不适用于: IP
  • 种属反应性
    与反应: Cow, Human
  • 免疫原

    This antibody was raised using the globular N terminal domain of clathrin heavy chain.

  • 阳性对照
    • Methanol fixed HeLa cells for IF.



Our Abpromise guarantee covers the use of ab24578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration. PubMed: 21571834
WB 1/250. Predicted molecular weight: 192 kDa.
ICC/IF Use at an assay dependent concentration.
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.
    • 序列相似性Belongs to the clathrin heavy chain family.
    • 细胞定位Cytoplasmic vesicle membrane. Membrane > coated pit. Melanosome. Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CHC17 antibody
      • Clathrin heavy chain antibody
      • Clathrin heavy chain 1 antibody
      • Clathrin heavy chain 2 antibody
      • Clathrin heavy chain like 1 antibody
      • Clathrin heavy chain on chromosome 17 antibody
      • Clathrin heavy polypeptide antibody
      • CLH 17 antibody
      • CLH 22 antibody
      • CLH-17 antibody
      • CLH1_HUMAN antibody
      • CLH17 antibody
      • CLH22 antibody
      • CLTC antibody
      • CLTCL antibody
      • CLTCL1 antibody
      • CLTCL2 antibody
      • CLTD antibody
      • Hc antibody
      • KIAA0034 antibody
      see all

    Anti-Clathrin heavy chain antibody [TD.1] 图像

    • ab24578 at a 1/200 dilution staining clathrin triskelion (blue) throughout the methanol fixed HeLa cells by Immunocytochemistry/Immunofluorescence. The Golgi is brilliantly stained by Giantin (yellow). Secondary antibodies used were a goat anti-mouse alexafluor AF546 and a goat anti-rabbit alexafluor AF488 applied at 1 ug/mL. The DNA was visualized with DAPI at 1 ug/mL. The colors of this image were altered.

    Anti-Clathrin heavy chain antibody [TD.1] (ab24578)参考文献

    This product has been referenced in:
    • Kitahara H  et al. COP35, a cholangiocarcinoma-binding oligopeptide, interacts with the clathrin heavy chain accompanied by GRP78. Mol Cancer Res 9:688-701 (2011). IHC-P ; Human . Read more (PubMed: 21571834) »
    • Harel A  et al. Evidence for CALM in directing VAMP2 trafficking. Traffic 9:417-29 (2008). Read more (PubMed: 18182011) »

    See all 5 Publications for this product

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