Anti-Clathrin heavy chain抗体(ab59710)
Key features and details
- Rabbit polyclonal to Clathrin heavy chain
- Suitable for: IHC-P
- Isotype: IgG
概述
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产品名称
Anti-Clathrin heavy chain抗体
参阅全部 Clathrin heavy chain 一抗 -
描述
兔多克隆抗体to Clathrin heavy chain -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
预测可用于: Chicken, Cow, Xenopus laevis, Caenorhabditis elegans, Zebrafish, a wide range of other species -
免疫原
Synthetic peptide corresponding to Rat Clathrin heavy chain aa 619-638.
Sequence:KAGLLQRALEHFTDLYDIKR
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阳性对照
- IHC-P: Non-ciliated bronchiolar cells (Clara cells).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.02% Thimerosal (merthiolate)
Constituent: Whole serum -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab59710于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use at an assay dependent concentration.
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说明 |
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IHC-P
Use at an assay dependent concentration. |
靶标
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功能
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. -
序列相似性
Belongs to the clathrin heavy chain family. -
细胞定位
Cytoplasmic vesicle membrane. Membrane > coated pit. Melanosome. Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
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数据库链接
- Entrez Gene: 281080 Cow
- Entrez Gene: 323579 Zebrafish
- SwissProt: P49951 Cow
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别名
- CHC17 antibody
- Clathrin heavy chain antibody
- Clathrin heavy chain 1 antibody
see all
图片
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ab59710 at 1/1000, overnight, secondary antibody biotinylated goat anti-sheep at 1/3000.
Figure A is a low power image showing intense staining of non-ciliated bronchiolar cells (Clara cells) and lesser staining in alveolar type II cells.
Figure B is a higher power image of the staining of the non ciliated bronchiolar cells.
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ab59710 at 1/100, overnight, secondary antibody donkey anti-rabbit Cy2® at 1/50. Confocal image shows intense staining of non-ciliated bronchiolar cells (Clara cells).
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab59710 被引用在 6 文献中.
- Ríos H et al. The role of PDLIM1, a PDZ-LIM domain protein, at the ribbon synapses in the chicken retina. J Comp Neurol 528:1820-1832 (2020). PubMed: 31930728
- Fu W et al. 17ß-Estradiol Inhibits PCSK9-Mediated LDLR Degradation Through GPER/PLC Activation in HepG2 Cells. Front Endocrinol (Lausanne) 10:930 (2019). PubMed: 32082252
- Eno C et al. aura (mid1ip1l) regulates the cytoskeleton at the zebrafish egg-to-embryo transition. Development 143:1585-99 (2016). PubMed: 26965374
- Garcin PO & Panté N Cell migration is another player of the minute virus of mice infection. Virology 468-470C:150-159 (2014). Mouse . PubMed: 25173091
- Fowler R et al. Uptake and transport of B12-conjugated nanoparticles in airway epithelium. J Control Release 172:374-81 (2013). ICC/IF ; Human . PubMed: 24008152
- Wahl S et al. A local, periactive zone endocytic machinery at photoreceptor synapses in close vicinity to synaptic ribbons. J Neurosci 33:10278-300 (2013). PubMed: 23785143