概述

  • 产品名称Anti-CKAP1抗体
    参阅全部 CKAP1 一抗
  • 描述
    兔多克隆抗体to CKAP1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 1-213 of Human CKAP1 (NP_001272).

  • 阳性对照
    • WB: 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates IHC-P: H1299 xenograft

性能

应用

Our Abpromise guarantee covers the use of ab96101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 27 kDa.
IHC-P 1/100 - 1/500.

靶标

  • 功能Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
  • 组织特异性Found in most tissues.
  • 序列相似性Belongs to the TBCB family.
    Contains 1 CAP-Gly domain.
  • 翻译后修饰Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.
    Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton. Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CG22 antibody
    • CKAPI antibody
    • Cytoskeleton associated protein 1 antibody
    • Cytoskeleton associated protein CKAPI antibody
    • Cytoskeleton-associated protein 1 antibody
    • Cytoskeleton-associated protein CKAPI antibody
    • Tbcb antibody
    • TBCB_HUMAN antibody
    • Tubulin folding cofactor B antibody
    • Tubulin specific chaperone B antibody
    • Tubulin-folding cofactor B antibody
    • Tubulin-specific chaperone B antibody
    see all

Anti-CKAP1 antibody 图像

  • All lanes : Anti-CKAP1 antibody (ab96101) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : Hela whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 27 kDa
  • ab96101, at a 1/500 dilution, staining CKAP1 in paraffin embedded H1299 xenograft by Immunohistochemical analysis.

Anti-CKAP1 antibody (ab96101)参考文献

ab96101 has not yet been referenced specifically in any publications.

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