概述

  • 产品名称Anti-CKAP1抗体
    参阅全部 CKAP1 一抗
  • 描述
    兔多克隆抗体to CKAP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Rabbit, Horse, Guinea pig, Cat, Dog, Human
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 37 - 86 (FKCKLELVVG SPASCMELEL GADDKFYSKL QEDALLGSYP DDGCRIH) of Mouse CKAP1 (NP_079824).

  • 阳性对照
    • Mouse thymus lysate

性能

应用

Our Abpromise guarantee covers the use of ab113962 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
  • 组织特异性Found in most tissues.
  • 序列相似性Belongs to the TBCB family.
    Contains 1 CAP-Gly domain.
  • 翻译后修饰Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.
    Ubiquitinated in the presence of GAN which targets it for degradation by the proteasome.
  • 细胞定位Cytoplasm. Cytoplasm > cytoskeleton. Colocalizes with microtubules. In differentiated neurons, located in the cytoplasm. In differentiating neurons, accumulates at the growth cone.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CG22 antibody
    • CKAPI antibody
    • Cytoskeleton associated protein 1 antibody
    • Cytoskeleton associated protein CKAPI antibody
    • Cytoskeleton-associated protein 1 antibody
    • Cytoskeleton-associated protein CKAPI antibody
    • Tbcb antibody
    • TBCB_HUMAN antibody
    • Tubulin folding cofactor B antibody
    • Tubulin specific chaperone B antibody
    • Tubulin-folding cofactor B antibody
    • Tubulin-specific chaperone B antibody
    see all

Anti-CKAP1 antibody 图像

  • Anti-CKAP1 antibody (ab113962) at 1 µg/ml + Mouse thymus lysate at 10 µg

    Predicted band size : 27 kDa

Anti-CKAP1 antibody (ab113962)参考文献

ab113962 has not yet been referenced specifically in any publications.

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