概述

  • 产品名称Anti-CITED4抗体
    参阅全部 CITED4 一抗
  • 描述
    兔多克隆抗体to CITED4
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 51-100 (PPPPGTLAYG SFGSPVSFQP FPVSQSPGAG STHLQSAATP SPGRIPAPPA) of Mouse CITED4 (NP_062509).

性能

应用

Our Abpromise guarantee covers the use of ab105797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 18 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells.
  • 组织特异性Expressed in most tissues examined with highest levels of expression in heart, liver, skeletal muscle and pancreas. Also expressed in bladder cell line ECV304 and in various breast cancer cell lines. Also detected in both in situ and invasive breast tumors where its expression is down-regulated and mostly restricted to the cytoplasm of malignant epithelium. Down-regulation of expression is associated with elevated levels of HIF1A and increased tumor growth and angiogenesis.
  • 序列相似性Belongs to the CITED family.
  • 细胞定位Nucleus. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AU019445 antibody
    • AW742964 antibody
    • Cbp/p300 interacting transactivator 4 antibody
    • cbp/p300 interacting transactivator, with glu/asp rich carboxy terminal domain, 4 antibody
    • Cbp/p300-interacting transactivator 4 antibody
    • CITE4_HUMAN antibody
    • Cited4 antibody
    • MRG 2 antibody
    • MRG-2 antibody
    • Mrg2 antibody
    • MSG1 related protein 2 antibody
    • MSG1-related protein 2 antibody
    • Transcriptional co-activator 4 antibody
    see all

Anti-CITED4 antibody 图像

  • Anti-CITED4 antibody (ab105797) (0.2-1 ug/ml) + Mouse Heart

    Predicted band size : 18 kDa

Anti-CITED4 antibody (ab105797)参考文献

ab105797 has not yet been referenced specifically in any publications.

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