Cisapride,5-HT4 receptor激动剂(ab120548)
Key features and details
- 5-HT4 receptor agonist. hERG blocker.
- CAS Number: 81098-60-4
- Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
Cisapride,5-HT4 receptor激动剂 -
描述
5-HT4 receptor激动剂. hERG blocker. -
生物学描述
5-HT4 receptor agonist (EC50 = 140 nM). Potent human ether-a-go-go-related gene (hERG) channel blocker (IC50 = 9.4 nM). Gastrokinetic agent, increases intestinal motility.
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CAS编号
81098-60-4 -
化学结构
性能
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化学名称
(±)-4-Amino-5-chloro-N-[1-[(3R*,4S*)-3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxybenzamide -
分子量
465.95 -
分子式
C23H29ClFN3O4 -
PubChem识别号
6917698 -
存放说明
Store at Room Temperature. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming) -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
Clc1cc(c(OC)cc1N)C(=O)N[C@@H]3CCN(CCCOc2ccc(F)cc2)C[C@@H]3OC -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
ab120548 尚未被引用在任何文献中。