概述

  • 产品名称Anti-Cirhin抗体
    参阅全部 Cirhin 一抗
  • 描述
    兔多克隆抗体to Cirhin
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the N-terminal region of Human Cirhin.

  • 阳性对照
    • Neuro-2a cell line lysates and Human brain tissue.

性能

应用

Our Abpromise guarantee covers the use of ab103357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 77 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 相关性Defects in Cirhin are the cause of North American Indian childhood cirrhosis. NAIC is a severe autosomal recessive intrahepatic cholestasis, originally described in Ojibway-Cree children from northwestern Quebec. NAIC typically presents with transient neonatal jaundice, in a child who is otherwise healthy, and progresses to biliary cirrhosis and portal hypertension. Biochemical and histopathological features suggest involvement of the bile ducts rather than of the bile canaliculi. They include elevated gamma glutamyltransferase and alkaline phosphatase levels, and, typically, marked fibrosis around bile ducts. Clinically, NAIC is distinct from other nonsyndromic familial cholestases because of its marked cholangiopathic features and severe degree of fibrosis on liver histology.
  • 细胞定位Nucleus; nucleolus
  • 数据库链接
  • 别名
    • CIRH1A antibody
    • Cirhin antibody
    • Cirrhosis, autosomal recessive 1A (cirhin) antibody
    • FLJ17146 antibody
    • KIAA1988 antibody
    • NAIC antibody
    • testis expressed gene 292 antibody
    • TEX292 antibody
    • UTP4 antibody
    • UTP4 small subunit (SSU) processome component homolog antibody
    see all

Anti-Cirhin antibody 图像

  • Anti-Cirhin antibody (ab103357) at 1/100 dilution + Neuro-2a cell lysate at 35 µg

    Predicted band size : 77 kDa
  • IHC analysis in formalin fixed and paraffin embedded Human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining, using ab103357 at a dilution of 1/50.

Anti-Cirhin antibody (ab103357)参考文献

ab103357 has not yet been referenced specifically in any publications.

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