概述

  • 产品名称Anti-CHX10抗体
    参阅全部 CHX10 一抗
  • 描述
    兔多克隆抗体to CHX10
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 250 - 350 of Human CHX10.

  • 阳性对照
    • This antibody gave a positive signal in Human liver tissue lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab93715 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).

靶标

  • 功能Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells.
  • 组织特异性Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate.
  • 疾病相关Defects in VSX2 are the cause of microphthalmia isolated type 2 (MCOP2) [MIM:610093]; also known as isolated clinical anophthalmia. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present.
    Defects in VSX2 are the cause of microphthalmia with cataracts and iris abnormalities (MCOPCTI) [MIM:610092].
    Defects in VSX2 are the cause of microphthalmia isolated with coloboma type 3 (MCOPCB3) [MIM:610092]; also known as isolated colobomatous microphthalmia 3. Ocular colobomas are a set of malformations resulting from abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure).
  • 序列相似性Belongs to the paired homeobox family.
    Contains 1 CVC domain.
    Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C elegans ceh 10 homeo domain containing homolog antibody
    • Ceh 10 homeo domain containing homolog (C. elegans) antibody
    • Ceh 10 homeo domain containing homolog antibody
    • Ceh 10 homeodomain containing homolog antibody
    • Ceh 10 homeodomain containing homolog (C. elegans) antibody
    • Ceh-10 homeodomain-containing homolog antibody
    • Ceh10 homeo domain containing homolog antibody
    • Ceh10 homeodomain containing homolog antibody
    • CHX 10 antibody
    • Homeobox protein CHX 10 antibody
    • Homeobox protein CHX10 antibody
    • HOX 10 antibody
    • HOX10 antibody
    • MCOP 2 antibody
    • MCOP2 antibody
    • MCOPCB 3 antibody
    • MCOPCB3 antibody
    • RET 1 antibody
    • RET1 antibody
    • Visual system homeobox 2 antibody
    • Vsx 2 antibody
    • Vsx2 antibody
    • VSX2_HUMAN antibody
    see all

Anti-CHX10 antibody 图像

  • Anti-CHX10 antibody (ab93715) at 1 µg/ml + Human liver tissue lysate - total protein (ab29889) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 39 kDa
    Observed band size : 39 kDa
    Additional bands at : 61 kDa,71 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 4 minutes

Anti-CHX10 antibody (ab93715)参考文献

ab93715 has not yet been referenced specifically in any publications.

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