Anti-CHTF18抗体(ab102076)

概述

  • 产品名称Anti-CHTF18抗体
    参阅全部 CHTF18 一抗
  • 描述
    兔多克隆抗体to CHTF18
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 755-804 (QALLLDALCL LLDILAPKLR PVSTQLYSTR EKQQLASLVG TMLAYSLTYR) of Human CHTF18 (NP_071375).

  • 阳性对照
    • Human fetal liver lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab102076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 107 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.
  • 序列相似性Belongs to the activator 1 small subunits family. CTF18 subfamily.
  • 细胞定位Nucleus. Associates with chromatin during S phase.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 6030457M03Rik antibody
    • C16orf41 antibody
    • C321D2.2 antibody
    • C321D2.3 antibody
    • C321D2.4 antibody
    • CHL12 antibody
    • chromosome transmission fidelity factor 18 homolog (S. cerevisiae) antibody
    • Chromosome transmission fidelity protein 18 homolog antibody
    • chtf18 antibody
    • Ctf18 antibody
    • CTF18_HUMAN antibody
    • hCTF18 antibody
    • MGC38008 antibody
    • RUVBL antibody
    see all

Anti-CHTF18 antibody 图像

  • Anti-CHTF18 antibody (ab102076) at 1 µg/ml + Human fetal liver lysate at 10 µg

    Predicted band size : 107 kDa

Anti-CHTF18 antibody (ab102076)参考文献

ab102076 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (HeLa)
Specification HeLa
Fixative Paraformaldehyde
Permeabilization Yes - 0.5% Triton X100
Username

Dr. Kirk McManus

Verified customer

提交于 Sep 16 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"