概述

  • 产品名称Anti-CHST3抗体
    参阅全部 CHST3 一抗
  • 描述
    小鼠单克隆抗体to CHST3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: VAFAGKYKTW KKWLDDEGQD GLREEEVQRL RGNCESIRLS AELGLRQPAW LRGRYMLVRY EDVARGPLQK AREMYRFAGI PLTPQVEDWI QKNTQAAHDG , corresponding to amino acids 312-412 of Human CHST3

性能

应用

Our Abpromise guarantee covers the use of ab56606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.
    • 组织特异性Widely expressed in adult tissues. Expressed in heart, placenta, skeletal muscle and pancreas. Also expressed in various immune tissues such as spleen, lymph node, thymus and appendix.
    • 疾病相关Defects in CHST3 are a cause of spondyloepiphyseal dysplasia with congenital joint dislocations (SEDC-JD) [MIM:143095]. A bone dysplasia clinically characterized by dislocation of the knees and/or hips at birth, clubfoot, elbow joint dysplasia with subluxation and limited extension, short stature, and progressive kyphosis developing in late childhood. The disorder is usually evident at birth, with short stature and multiple joint dislocations or subluxations that dominate the neonatal clinical and radiographic picture. During childhood, the dislocations improve, both spontaneously and with surgical treatment, and features of spondyloepiphyseal dysplasia become apparent, leading to arthritis of the hips and spine with intervertebral disk degeneration, rigid kyphoscoliosis, and trunk shortening by late childhood.
    • 序列相似性Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
    • 细胞定位Golgi apparatus membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C6ST 1 antibody
      • C6ST antibody
      • C6ST-1 antibody
      • C6ST1 antibody
      • Carbohydrate (chondroitin 6) sulfotransferase 3 antibody
      • Carbohydrate sulfotransferase 3 antibody
      • Chondroitin 6 O sulfotransferase 1 antibody
      • Chondroitin 6 sulfotransferase antibody
      • Chondroitin 6-O-sulfotransferase 1 antibody
      • Chondroitin 6-sulfotransferase antibody
      • CHST 3 antibody
      • Chst3 antibody
      • CHST3_HUMAN antibody
      • Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 0 antibody
      • Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0 antibody
      • GST 0 antibody
      • GST-0 antibody
      • GST0 antibody
      see all

    Anti-CHST3 antibody 图像



    • Predicted band size : 55 kDa
      CHST3 antibody (ab56606) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-CHST3 antibody (ab56606)参考文献

    ab56606 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56606.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"