Anti-Chromogranin A抗体[LK2H10 + PHE5] (ab715)


  • 产品名称Anti-Chromogranin A抗体[LK2H10 + PHE5]
    参阅全部 Chromogranin A 一抗
  • 描述
    小鼠单克隆抗体[LK2H10 + PHE5] to Chromogranin A
  • 经测试应用适用于: ICC/IF, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Rat, Human, Monkey
  • 免疫原

    Human pheochromocytoma

  • 表位Although the epitopes for these two clones are not precisely mapped, experimental data suggest that they are different.
  • 阳性对照
    • Pancreas, adrenal gland, bowel and thyroid
  • 常规说明This antibody is a mixture of two clones, LK2H10 and PHE5.



Our Abpromise guarantee covers the use of ab715 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration.
IHC-P 1/50 - 1/100.
IHC-Fr Use at an assay dependent concentration.


  • 功能Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • 序列相似性Belongs to the chromogranin/secretogranin protein family.
  • 翻译后修饰Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • 细胞定位Secreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt
  • 数据库链接
  • 形式According to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
  • 别名
    • beta Granin antibody
    • betagranin (N-terminal fragment of chromogranin A) antibody
    • catestatin antibody
    • CgA antibody
    • CHG A antibody
    • Chga antibody
    • chromofungin antibody
    • Chromogranin A antibody
    • Chromogranin A parathyroid secretory protein 1 antibody
    • Chromogranin A precursor antibody
    • ChromograninA antibody
    • CMGA_HUMAN antibody
    • ER-37 antibody
    • Pancreastatin antibody
    • Parastatin antibody
    • Parathyroid secretory protein 1 antibody
    • Pituitary secretory protein I antibody
    • Secretory protein I antibody
    • SP I antibody
    • SP-I antibody
    • SP1 antibody
    • SPI antibody
    • Vasostatin antibody
    • Vasostatin I antibody
    • Vasostatin II antibody
    see all

Anti-Chromogranin A antibody [LK2H10 + PHE5] 图像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of neuroendocrine tumor tissue labeling Chromogranin A with ab715.

  • Immunocytochemistry/ Immunofluorescence analysis of human prostate cells labeling Chromogranin A with ab715 at 1/200 dilution (green). Cells were fixed with 4% paraformaldehyde and permeabilized with 0.8% Triton X-100. A donkey anti-mouse (Alexa Fluor® 647) was used as the secondary antibody at 1/400 dilution.

    See Abreview

Anti-Chromogranin A antibody [LK2H10 + PHE5] (ab715)参考文献

This product has been referenced in:
  • Burke AP  et al. Carcinoids of the jejunum and ileum: an immunohistochemical and clinicopathologic study of 167 cases. Cancer 79:1086-93 (1997). Read more (PubMed: 9070484) »
  • Angelsen A  et al. Neuroendocrine differentiation in carcinomas of the prostate: do neuroendocrine serum markers reflect immunohistochemical findings? Prostate 30:1-6 (1997). Read more (PubMed: 9018329) »

See all 8 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (Prostate)
Specification Prostate
Fixative Paraformaldehyde
Permeabilization Yes - 0.8% Triton X-100
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 20% · Temperature: 24°C

Abcam user community

Verified customer

提交于 Jan 04 2008

Thank you for your enquiry and patience. I have confirmed with the laboratory that the ab715 antibody's concentration is 200ug/ml and the purification is by protein G chromatography. I hope this information will be useful to you. If you require a...

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Thank you for your enquiry. Unfortunately, we do not have more information about this antibody. We will update the on-line datasheet of this product as soon as we get more data. We apologize for any inconvenience caused. If you have any questions in th...

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