概述

  • 产品名称Anti-Chromogranin A抗体[LK2H10]
    参阅全部 Chromogranin A 一抗
  • 描述
    小鼠单克隆抗体[LK2H10] to Chromogranin A
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Rat, Rabbit, Human, Pig, Monkey
  • 免疫原

    Human pheochromocytoma.

  • 阳性对照
    • PC-12 cells. Pancreas.

性能

应用

Our Abpromise guarantee covers the use of ab80787 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 68 kDa (predicted molecular weight: 51 kDa).
IHC-P 1/800. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Use of a high-sensitivity detection system.

靶标

  • 功能Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • 序列相似性Belongs to the chromogranin/secretogranin protein family.
  • 翻译后修饰Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • 细胞定位Secreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt
  • 数据库链接
  • 形式According to the Swiss-Prot database, this protein has many different forms which correspond to various molecular weights; thus the possible variation from the predicted molecular weight of 51kDa.
  • 别名
    • beta Granin antibody
    • betagranin (N-terminal fragment of chromogranin A) antibody
    • catestatin antibody
    • CgA antibody
    • CHG A antibody
    • Chga antibody
    • chromofungin antibody
    • Chromogranin A parathyroid secretory protein 1 antibody
    • Chromogranin A precursor antibody
    • ChromograninA antibody
    • CMGA_HUMAN antibody
    • ER-37 antibody
    • Pancreastatin antibody
    • Parastatin antibody
    • Parathyroid secretory protein 1 antibody
    • Pituitary secretory protein I antibody
    • Secretory protein I antibody
    • SP I antibody
    • SP-I antibody
    • SP1 antibody
    • SPI antibody
    • Vasostatin antibody
    • Vasostatin I antibody
    • Vasostatin II antibody
    see all

Anti-Chromogranin A antibody [LK2H10] 图像

  • Formalin-fixed, paraffin-embedded human pancreatic tumor stained with ab80787 at a 1/800 dilution using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.
  • Formalin-fixed, paraffin-embedded rat pancreas stained with ab80787 at a 1/800 dilution using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of islet cells.
  • Anti-Chromogranin A antibody [LK2H10] (ab80787) at 2 µg/ml + PC12 cells

    Predicted band size : 51 kDa
    Observed band size : 68 kDa (why is the actual band size different from the predicted?)

Anti-Chromogranin A antibody [LK2H10] (ab80787)参考文献

This product has been referenced in:
  • Lloyd RV & Wilson BS Specific endocrine tissue marker defined by a monoclonal antibody. Science 222:628-30 (1983). WB, IHC-P ; Human, Rat, Monkey, Pig, Rabbit . Read more (PubMed: 6635661) »

See 1 Publication for this product

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