概述

  • 产品名称Anti-CHRNA10抗体
    参阅全部 CHRNA10 一抗
  • 描述
    兔多克隆抗体to CHRNA10
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from Human CHRNA10.

  • 阳性对照
    • Extracts from A549 cells, COLO cells, HeLa cells and 293 cells

性能

应用

Our Abpromise guarantee covers the use of ab110063 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 50 kDa.

靶标

  • 功能Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
  • 组织特异性Expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-10/CHRNA10 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody
    • ACH10_HUMAN antibody
    • Alpha 10 nAChR antibody
    • Cholinergic receptor nicotinic alpha 10 antibody
    • Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody
    • Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody
    • CHRNA 10 antibody
    • CHRNA10 antibody
    • NACHR alpha 10 antibody
    • NACHR alpha-10 antibody
    • NACHRA10 antibody
    • Neuronal acetylcholine receptor protein subunit alpha 10 antibody
    • Neuronal acetylcholine receptor subunit alpha-10 antibody
    • Nicotinic acetylcholine receptor subunit alpha 10 antibody
    • Nicotinic acetylcholine receptor subunit alpha-10 antibody
    • OTTHUMP00000013620 antibody
    see all

Anti-CHRNA10 antibody 图像

  • All lanes : Anti-CHRNA10 antibody (ab110063) at 1/500 dilution

    Lane 1 : Extracts from A549 cells
    Lane 2 : Extracts from COLO cells
    Lane 3 : Extracts from 293 cells
    Lane 4 : Extracts from HeLa cells
    Lane 5 : Extracts from A549 cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 50 kDa

Anti-CHRNA10 antibody (ab110063)参考文献

ab110063 has not yet been referenced specifically in any publications.

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