概述

  • 产品名称
  • 描述
    兔多克隆抗体to CHRDL1
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, between amino acids 5-35 from the N-terminal region of Human CHRDL1 (NP_660277).

  • 阳性对照
    • 293 cell line lysate, Human hepatocarcinoma tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab107008 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab107008 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 51 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.
  • 组织特异性
    Expressed in retinal pericytes.
  • 序列相似性
    Contains 3 VWFC domains.
  • 细胞定位
    Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CHL antibody
    • chordin like 1 antibody
    • Chordin-like protein 1 antibody
    • CHRDL1 antibody
    • CRDL1_HUMAN antibody
    • dA141H5.1 antibody
    • neuralin 1 antibody
    • Neuralin-1 antibody
    • Neurogenesin-1 antibody
    • NRLN1 antibody
    • Ventroptin antibody
    • VOPT antibody
    see all

图片

  • Anti-CHRDL1 antibody (ab107008) at 1/100 dilution + 293 cell line lysate at 35 µg

    Predicted band size : 51 kDa
  • Immunohistochemistry analysis in formalin fixed and paraffin embedded Human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. ab107008 at a dilution of 1/50.

文献

ab107008 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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