概述

  • 产品名称Anti-CHN 1抗体
    参阅全部 CHN 1 一抗
  • 描述
    小鼠单克隆抗体to CHN 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 91-201 of Human CHN 1

性能

应用

Our Abpromise guarantee covers the use of ab54610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能GTPase-activating protein for p21-rac and a phorbol ester receptor. May play an important role in neuronal signal-transduction mechanisms.
    • 组织特异性In neurons in brain regions that are involved in learning and memory processes.
    • 疾病相关Defects in CHN1 are the cause of Duane retraction syndrome type 2 (DURS2) [MIM:604356]. Duane retraction syndrome is a congenital eye movement disorder characterized by a failure of cranial nerve VI (the abducens nerve) to develop normally, resulting in restriction or absence of abduction, adduction, or both, and narrowing of the palpebral fissure and retraction of the globe on attempted adduction. Undiagnosed in children, it can lead to amblyopia, a permanent uncorrectable loss of vision.
    • 序列相似性Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 Rho-GAP domain.
      Contains 1 SH2 domain.
    • 发展阶段Increases in amount during brain development coincident with synaptogenesis.
    • Information by UniProt
    • 数据库链接
    • 别名
      • A-chimaerin antibody
      • Alpha-chimerin antibody
      • ARHGAP2 antibody
      • CHIN_HUMAN antibody
      • CHN antibody
      • Chn1 antibody
      • N chimaerin antibody
      • N chimerin antibody
      • N-chimaerin antibody
      • N-chimerin antibody
      • NC antibody
      • Rho GTPase-activating protein 2 antibody
      • RHOGAP2 antibody
      see all

    Anti-CHN 1 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab54610 CHN 1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-CHN 1 antibody (ab54610)参考文献

    ab54610 has not yet been referenced specifically in any publications.

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