概述

  • 产品名称Anti-CHL1抗体
    参阅全部 CHL1 一抗
  • 描述
    兔多克隆抗体to CHL1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 450 - 550 of Mouse CHL1.

  • 阳性对照
    • This antibody gave a positive signal in the following mouse tissue lysates: Cerebellum; Spinal Cord; Retina; Optic Nerve.

性能

应用

Our Abpromise guarantee covers the use of ab93197 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 220 kDa (predicted molecular weight: 135 kDa).

靶标

  • 相关性CHL1 is an extracellular matrix and cell adhesion protein that plays a role in nervous system development and in synaptic plasticity. Both soluble and membranous forms promote neurite outgrowth of cerebellar and hippocampal neurons and suppress neuronal cell death. CHL1 plays a role in neuronal positioning of pyramidal neurons and in regulation of both the number of interneurons and the efficacy of GABAergic synapses. CHL1 may play a role in regulating cell migration in nerve regeneration and cortical development. Potentiates integrin-dependent cell migration towards extracellular matrix proteins and recruits ANK3 to the plasma membrane.
  • 细胞定位Cell Membrane and Secreted
  • 数据库链接
  • 别名
    • CALL antibody
    • Cell adhesion molecule with homology to L1CAM (close homolog of L1) antibody
    • Cell adhesion molecule with homology to L1CAM (close homologue of L1) antibody
    • Cell adhesion molecule with homology to L1CAM antibody
    • Close homolog of L1 antibody
    • FLJ44930 antibody
    • L1 cell adhesion molecule 2 antibody
    • L1CAM2 antibody
    • MGC132578 antibody
    • Neural cell adhesion molecule antibody
    see all

Anti-CHL1 antibody 图像

  • All lanes : Anti-CHL1 antibody (ab93197) at 1 µg/ml

    Lane 1 : Cerebellum (Mouse) Tissue Lysate
    Lane 2 : Spinal Cord (Mouse) Tissue Lysate
    Lane 3 : Retina (Mouse) Tissue Lysate
    Lane 4 : Optic Nerve (Mouse) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 135 kDa
    Observed band size : 220 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 125 kDa,140 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

Anti-CHL1 antibody (ab93197)参考文献

ab93197 has not yet been referenced specifically in any publications.

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