Anti-FOXN3抗体[CHESC9H4] (ab50756)
Key features and details
- Mouse monoclonal [CHESC9H4] to FOXN3
- Suitable for: Dot blot, WB
- Reacts with: Recombinant fragment
- Isotype: IgG1
概述
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产品名称
Anti-FOXN3抗体[CHESC9H4]
参阅全部 FOXN3 一抗 -
描述
小鼠单克隆抗体[CHESC9H4] to FOXN3 -
宿主
Mouse -
经测试应用
适用于: Dot blot, WBmore details -
种属反应性
与反应: Recombinant fragment
预测可用于: Human -
免疫原
Recombinant fragment corresponding to FOXN3.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
Purified using protein G column chromatography from culture supernatant of hybridoma cultured in a meium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. Filtered through a 0.22 micrometer membrane. -
克隆
单克隆 -
克隆编号
CHESC9H4 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab50756于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Dot blot |
Use at an assay dependent concentration.
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WB | (2) |
Use at an assay dependent concentration.
|
说明 |
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Dot blot
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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功能
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). -
序列相似性
Contains 1 fork-head DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 1112 Human
- Omim: 602628 Human
- SwissProt: O00409 Human
- Unigene: 434286 Human
- Unigene: 621371 Human
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别名
- C14orf116 antibody
- Checkpoint suppressor 1 antibody
- CHES1 antibody
see all
数据表及文件
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Datasheet download
文献 (3)
ab50756 被引用在 3 文献中.
- Xue W et al. FOXN3 is downregulated in osteosarcoma and transcriptionally regulates SIRT6, and suppresses migration and invasion in osteosarcoma. Oncol Rep 41:1404-1414 (2019). PubMed: 30483801
- Sun J et al. The transcription factor FOXN3 inhibits cell proliferation by downregulating E2F5 expression in hepatocellular carcinoma cells. Oncotarget 7:43534-43545 (2016). WB . PubMed: 27259277
- Huot G et al. CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis. Mol Biol Cell 25:554-65 (2014). PubMed: 24403608