概述

  • 产品名称
    Anti-Chemokine Receptor D6抗体
    参阅全部 Chemokine Receptor D6 一抗
  • 描述
    兔多克隆抗体to Chemokine Receptor D6
  • 宿主
    Rabbit
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide within Human Chemokine Receptor D6 aa 1-100 (N terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.

  • 阳性对照
    • Human breast carcinoma and hepatocarcinoma tissue and mouse liver tissue lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    ab38567 was purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab38567 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 43 kDa (predicted molecular weight: 40 kDa).

靶标

  • 功能
    Receptor for C-C type chemokines including SCYA2/MCP-1, SCY3/MIP-1-alpha, SCYA5/RANTES and SCYA7/MCP-3.
  • 组织特异性
    Expressed primarily in placenta and fetal liver, and found at very low levels in the lung and lymph node. Found in endothelial cells lining afferent lymphatics in dermis and lymph nodes. Also found in lymph nodes subcapsular and medullary sinuses, tonsillar lymphatic sinuses and lymphatics in mucosa and submucosa of small and large intestine and appendix. Also found in some malignant vascular tumors.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C C chemokine receptor D6 antibody
    • C-C chemokine receptor D6 antibody
    • CC chemokine binding receptor JAB61 antibody
    • CC chemokine receptor D6 antibody
    • CCBP 2 antibody
    • CCBP2 antibody
    • CCBP2_HUMAN antibody
    • CCR 10 antibody
    • CCR 9 antibody
    • CCR10 antibody
    • CCR9 antibody
    • Chemokine (C C motif) receptor 9 antibody
    • Chemokine (C C) receptor 9 antibody
    • Chemokine binding protein 2 antibody
    • Chemokine binding protein D6 antibody
    • Chemokine C C motif receptor 9 antibody
    • Chemokine C C receptor 9 antibody
    • Chemokine CC motif receptor 9 antibody
    • Chemokine CC receptor 9 antibody
    • Chemokine receptor 9 antibody
    • Chemokine receptor CCR 10 antibody
    • Chemokine receptor CCR 9 antibody
    • Chemokine receptor CCR-10 antibody
    • Chemokine receptor CCR-9 antibody
    • Chemokine receptor CCR10 antibody
    • Chemokine receptor CCR9 antibody
    • Chemokine receptor D6 antibody
    • Chemokine-binding protein 2 antibody
    • Chemokine-binding protein D6 antibody
    • CMKBR 9 antibody
    • CMKBR9 antibody
    • D6 antibody
    • hD6 antibody
    • MGC126678 antibody
    • MGC138250 antibody
    see all

图片

  • Anti-Chemokine Receptor D6 antibody (ab38567) at 1/500 dilution + Mouse liver tissue lysate

    Predicted band size: 40 kDa
    Observed band size: 43 kDa (why is the actual band size different from the predicted?)
    Additional bands at: 27 kDa, 80 kDa. We are unsure as to the identity of these extra bands.

  • Formalin fixed and paraffin embedded human breast carcinoma tissue stained with ab38567, followed by AEC staining.

实验方案

文献

This product has been referenced in:
  • Xu Z  et al. C-C Motif Chemokine Receptor 9 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction. J Am Heart Assoc 5:N/A (2016). Read more (PubMed: 27146447) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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