概述

  • 产品名称Anti-CHD4抗体
    参阅全部 CHD4 一抗
  • 描述
    兔多克隆抗体to CHD4
  • 经测试应用适用于: IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide against an internal sequence of Human CHD4 (Q14839).

  • 阳性对照
    • HepG2 cells and human liver carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab110971 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

靶标

  • 功能Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.
  • 序列相似性Belongs to the SNF2/RAD54 helicase family.
    Contains 2 chromo domains.
    Contains 1 helicase ATP-binding domain.
    Contains 1 helicase C-terminal domain.
    Contains 2 PHD-type zinc fingers.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus. Cytoplasm > cytoskeleton > centrosome. Associates with centrosomes in interphase.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ATP dependent helicase CHD4 antibody
    • ATP-dependent helicase CHD4 antibody
    • CHD 4 antibody
    • CHD-4 antibody
    • CHD4 antibody
    • CHD4_HUMAN antibody
    • Chromodomain helicase DNA binding protein 4 antibody
    • Chromodomain-helicase-DNA-binding protein 4 antibody
    • Mi 2 autoantigen 218 kDa protein antibody
    • Mi 2b antibody
    • Mi-2 autoantigen 218 kDa protein antibody
    • Mi2 beta antibody
    • Mi2-beta antibody
    see all

Anti-CHD4 antibody 图像

  • Immunofluorescence analysis of HepG2 cells, using CHD4 antibody (ab110971). On the left without blocking peptide and on the right with blocking peptide.
  • Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using CHD4 antibody (ab110971). On the left without blocking peptide and on the right with blocking peptide.

Anti-CHD4 antibody (ab110971)参考文献

ab110971 has not yet been referenced specifically in any publications.

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