概述

  • 产品名称Anti-CFHR5抗体
    参阅全部 CFHR5 一抗
  • 描述
    兔多克隆抗体to CFHR5
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-569 of Human CFHR5 (NP_110414.1).

  • 阳性对照
    • CFHR5 transfected 293T cell line.

性能

应用

Our Abpromise guarantee covers the use of ab118122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 64 kDa.
IP Use at an assay dependent dilution.

靶标

  • 功能Involved in complement regulation.
  • 组织特异性Expressed by the liver and secreted in plasma.
  • 疾病相关Note=Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. Atypical hemolytic uremic syndrome is a complex genetic disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure and absence of episodes of enterocolitis and diarrhea. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease. Susceptibility to the development of atypical hemolytic uremic syndrome can be conferred by mutations in various components of or regulatory factors in the complement cascade system. Other genes may play a role in modifying the phenotype.
  • 序列相似性Contains 9 Sushi (CCP/SCR) domains.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CFHL5 antibody
    • CFHR5 antibody
    • CFHR5D antibody
    • Complement factor H-related 5 antibody
    • Complement factor H-related protein 5 antibody
    • factor H-related gene 5 antibody
    • factor H-related protein 5 antibody
    • FHR-5 antibody
    • FHR5 antibody
    • FHR5_HUMAN antibody
    • FLJ10549 antibody
    • MGC133240 antibody
    • OTTHUMP00000034672 antibody
    see all

Anti-CFHR5 antibody 图像

  • All lanes : Anti-CFHR5 antibody (ab118122) at 1/1000 dilution

    Lane 1 : 293T cell line, transfected with CFHR5
    Lane 2 : 293T cell line, non-transfected

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 64 kDa
  • Immunoprecipitation of CFHR5 transfected lysate using ab118122 antibody and Protein A Magnetic Beads, immunoblotted with ab118122.

Anti-CFHR5 antibody (ab118122)参考文献

ab118122 has not yet been referenced specifically in any publications.

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