概述

  • 产品名称
  • 描述
    小鼠多克隆抗体to CES2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-623 of Human CES2 (NP_003860.2).

  • 阳性对照
    • Human liver tissue lysate and cell lysate from CES2 transfected 293T cells.

性能

应用

Our Abpromise guarantee covers the use of ab88439 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 62 kDa.

靶标

  • 功能
    Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methyumbelliferyl acetate, heroin and 6-monoacetylmorphine.
  • 组织特异性
    Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.
  • 序列相似性
    Belongs to the type-B carboxylesterase/lipase family.
  • 翻译后修饰
    Glycosylated.
  • 细胞定位
    Endoplasmic reticulum lumen.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Carboxylesterase 2 (intestine, liver) antibody
    • Carboxylesterase 2 antibody
    • CE-2 antibody
    • CES2 antibody
    • CES2A1 antibody
    • Cocaine esterase antibody
    • EC 3.1.1.1 antibody
    • EST2_HUMAN antibody
    • hCE-2 antibody
    • ICE antibody
    • Iintestinal carboxylesterase liver carboxylesterase 2 antibody
    • Intestinal carboxylesterase; liver carboxylesterase-2 antibody
    • Methylumbelliferyl acetate deacetylase 2 antibody
    • PCE 2 antibody
    • PCE-2 antibody
    see all

图片

  • Anti-CES2 antibody (ab88439) at 1 µg/ml + human liver tissue lysate at 25 µg
    Developed using the ECL technique

    Predicted band size : 62 kDa
    Observed band size : 62 kDa
  • All lanes : Anti-CES2 antibody (ab88439) at 1 µg/ml

    Lane 1 : cell lysate from CES2 transfected 293T cells
    Lane 2 : cell lysate from non transfected 293 T cells

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 62 kDa
    Observed band size : 62 kDa

实验方案

文献

ab88439 has not yet been referenced specifically in any publications.

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