Anti-Ceramide synthase 1抗体(ab85696)

概述

  • 产品名称Anti-Ceramide synthase 1抗体
    参阅全部 Ceramide synthase 1 一抗
  • 描述
    山羊多克隆抗体to Ceramide synthase 1
  • 特异性ab85696 is expected to recognize both reported isoforms (NP_067090.1 and NP_937850.1).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide:

    C-KDLREYDTAEAQ

    , corresponding to internal sequence amino acids 318-329 of Human LASS1 (NP_067090.1; NP_937850.1).

  • 阳性对照
    • Human brain (cerebellum, cerebral cortex and frontal cortex) lysates.

性能

应用

Our Abpromise guarantee covers the use of ab85696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 40 kDa).

靶标

  • 功能May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner.
  • 序列相似性Contains 1 TLC (TRAM/LAG1/CLN8) domain.
  • 细胞定位Endoplasmic reticulum membrane and Endoplasmic reticulum membrane. Golgi apparatus membrane. Isoform 1 may recycle from the Golgi to the endoplasmic reticulum.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Ceramide synthase 1 antibody
    • CerS1 antibody
    • CERS1_HUMAN antibody
    • LAG1 antibody
    • LAG1 homolog ceramide synthase 1 antibody
    • LAG1 longevity assurance homolog 1 antibody
    • LASS 1 antibody
    • LASS1 antibody
    • Longevity assurance (LAG1 S. cerevisiae) homolog 1 antibody
    • Longevity assurance gene 1 antibody
    • Longevity assurance gene 1 protein homolog 1 antibody
    • MGC90349 antibody
    • Protein LAG1 antibody
    • Protein UOG 1 antibody
    • Protein UOG-1 antibody
    • UOG 1 protein antibody
    • UOG1 antibody
    • Upstream of GDF1 antibody
    see all

Anti-Ceramide synthase 1 antibody 图像

  • Anti-Ceramide synthase 1 antibody (ab85696) at 1 µg/ml + Human Frontal cortex lysate (in RIPA buffer) at 35 µg

    Predicted band size : 40 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 85 kDa. We are unsure as to the identity of these extra bands.

Anti-Ceramide synthase 1 antibody (ab85696)参考文献

ab85696 has not yet been referenced specifically in any publications.

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