产品名称 Anti-CENTB1抗体 参阅全部 CENTB1 一抗
WB, ELISA, IHC-P more details
Mouse, Rat, Cow
C-EKLSRRSHDLHTL , corresponding to C terminal amino acids 728-740 of Human CENTB1
Jurkat lysate; Human tonsil tissue.
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration information loading...
纯度 Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明 ELISA: 1/32000.
IHC-P: Use at a concentration of 5 µg/ml.
WB: Use at a concentration of 0.5 - 2 µg/ml for 1hr. Detects a band of approximately 85 kDa (predicted molecular weight: 85 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能 GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.
组织特异性 Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
序列相似性 Contains 3 ANK repeats. Contains 1 Arf-GAP domain. Contains 1 BAR domain. Contains 1 PH domain.
结构域 PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate ACAP1-binding to PIP2 or PIP3 containing membranes.
翻译后修饰 Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Information by UniProt
ACAP 1 antibody
Anti-CENTB1 antibody 图像
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CENTB1 antibody (ab85945)
ab85945 at 5µg/ml staining CENTB1 in human tonsil by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.
Western blot - CENTB1 antibody (ab85945)
Anti-CENTB1 antibody (ab85945) at 0.5 µg/ml + Jurkat lysate at 35 µg Predicted band size : 85 kDa Observed band size : 85 kDa
Anti-CENTB1 antibody (ab85945)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"