存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 0.5mg/ml Tris saline. pH 7.3
Concentration information loading...
纯度 Immunogen affinity purified
Immunizing Peptide (Blocking)
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 80-90 kDa (predicted molecular weight: 85 kDa).Can be blocked with
Human CENTB1 peptide (ab23280).
功能 GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.
组织特异性 Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
序列相似性 Contains 3 ANK repeats. Contains 1 Arf-GAP domain. Contains 1 BAR domain. Contains 1 PH domain.
结构域 PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate ACAP1-binding to PIP2 or PIP3 containing membranes.
翻译后修饰 Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Information by UniProt
ACAP 1 antibody
Anti-CENTB1 antibody 图像
Western blot - CENTB1 antibody (ab15903)
Anti-CENTB1 antibody (ab15903) at 1 µg/ml + Jurkat cell lysate at 35 µg Predicted band size : 85 kDa Additional bands at : 80 kDa. We are unsure as to the identity of these extra bands.
Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Anti-CENTB1 antibody (ab15903)参考文献
has not yet been referenced specifically in any publications.
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