概述

  • 产品名称Anti-CENPQ抗体
    参阅全部 CENPQ 一抗
  • 描述
    兔多克隆抗体to CENPQ
  • 特异性Cross-reactivity with CENPQ from other sources has not been determined.
  • 经测试应用适用于: WB, ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Macaque Monkey
  • 免疫原

    Recombinant full length Human CENPQ (NP_060602.2).

  • 阳性对照
    • HeLa whole cell lysate and HeLa cells transfected with control sh-virus.

性能

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应用

Our Abpromise guarantee covers the use of ab105742 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 31 kDa.
ELISA 1/5000 - 1/20000.
ICC/IF 1/100.

靶标

  • 功能Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
  • 细胞定位Nucleus. Chromosome > centromere. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CENP Q antibody
    • CENP-Q antibody
    • Cenpq antibody
    • CENPQ_HUMAN antibody
    • Centromere protein Q antibody
    • FLJ10545 antibody
    • OTTHUMP00000016579 antibody
    see all

Anti-CENPQ antibody 图像

  • All lanes : Anti-CENPQ antibody (ab105742) at 0.5 µg/ml

    Lane 1 : Lysates from HeLa cells transfected with control sh-virus
    Lane 2 : Lysates from HeLa cells transfected with CENPQ sh-virus


    Predicted band size : 31 kDa
  • Immunofluorescence microscopy using ab105742 shows detection of endogenous CENPQ in HeLa whole cell lysate. Primary antibody was used at 1:100 followed by secondary antibody diluted 1:150. Red punctate anti-CENPQ signal colocalizes in overlay images with green punctate anti-CREST signals at the kinetochores (attached points of sister chromatids). Visible are colocalized CENPQ and CREST signal at various stages of the cell cycle as indicated from interphase to the end of mitosis. Nuclei are counter stained with bisbenzimide.

Anti-CENPQ antibody (ab105742)参考文献

ab105742 has not yet been referenced specifically in any publications.

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