Anti-CENPN抗体(ab57660)

概述

  • 产品名称Anti-CENPN抗体
    参阅全部 CENPN 一抗
  • 描述
    小鼠单克隆抗体to CENPN
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-205 of Human BM039

性能

应用

Our Abpromise guarantee covers the use of ab57660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
    • 细胞定位Nucleus. Chromosome > centromere > kinetochore. Localizes exclusively in the kinetochore domain of centromeres. Kinetochore-bound levels decrease when cells enter mitosis and increase again when cells exit mitosis.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BM 039 antibody
      • BM 309 antibody
      • BM-309 antibody
      • BM039 antibody
      • C16orf60 antibody
      • CENP N antibody
      • CENP-N antibody
      • Cenpn antibody
      • CENPN_HUMAN antibody
      • Centromere protein N antibody
      • FLJ13607 antibody
      • FLJ22660 antibody
      • ICEN 32 antibody
      • ICEN32 antibody
      • Interphase centromere complex protein 32 antibody
      see all

    Anti-CENPN antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57660 BM039 antibody at 1ug/ml. Predicted band size of immunogen is 49 kDa

    Anti-CENPN antibody (ab57660)参考文献

    ab57660 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us. I am sorry to read that this antibody is not working for you. Can you please describe for me your samples (species, tissue or cell type, and preparation) and how you block the membrane before applying the antibody? How much...

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    As requested, I have issued a free of charge replacement, ab104299, anti- CENP-N.

    To check the status of the order please contact our Customer Service team and reference this number.

    Please note that this free of charge replacemen...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"