概述

  • 产品名称Anti-CENPN抗体
    参阅全部 CENPN 一抗
  • 描述
    兔多克隆抗体to CENPN
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 309-339 of Human BM039.

  • 阳性对照
    • MCF-7 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab104296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Predicted molecular weight: 40 kDa.

靶标

  • 功能Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
  • 细胞定位Nucleus. Chromosome > centromere > kinetochore. Localizes exclusively in the kinetochore domain of centromeres. Kinetochore-bound levels decrease when cells enter mitosis and increase again when cells exit mitosis.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BM 039 antibody
    • BM 309 antibody
    • BM-309 antibody
    • BM039 antibody
    • C16orf60 antibody
    • CENP N antibody
    • CENP-N antibody
    • Cenpn antibody
    • CENPN_HUMAN antibody
    • Centromere protein N antibody
    • FLJ13607 antibody
    • FLJ22660 antibody
    • ICEN 32 antibody
    • ICEN32 antibody
    • Interphase centromere complex protein 32 antibody
    see all

Anti-CENPN antibody 图像

  • Anti-CENPN antibody (ab104296) at 1/50 dilution + MCF7 cell lysate at 35 µg

    Predicted band size : 40 kDa

Anti-CENPN antibody (ab104296)参考文献

ab104296 has not yet been referenced specifically in any publications.

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