概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 序列HASSGKDVPECKTQ

技术指标

Our Abpromise guarantee covers the use of ab45476 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • CENP E
    • Centromere associated protein E
    • Centromere autoantigen E
    • Centromere autoantigen E (312kD)
    • Centromere protein E
    • Centromere protein E 312kDa
    • KIF10
    • Kinesin family member 10
    • Kinesin related protein
    • Kinesin related protein CENPE
    • PPP1R61
    • Protein phosphatase 1, regulatory subunit 61
    see all
  • 相关性CENPE is a 250-300 kDa human centromere-associated kinesin-like motor protein that accumulates in G2 phase. In contrast to other centromere proteins, CENPE is not detected at centromeres during interphase, and first appears at the centromere region of chromosomes during prometaphase. CENPE function is required for the transition from metaphase to anaphase. CENPE is probably one of the motors responsible for mammalian chromosome movement and/or spindle elongation.
  • 细胞定位Associates with kinetochores during congression, relocates to the spindle midzone at anaphase, and is quantitatively discarded at the end of the cell division.

CENPE peptide (ab45476)参考文献

ab45476 has not yet been referenced specifically in any publications.

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