概述

  • 产品名称Anti-CED6抗体
    参阅全部 CED6 一抗
  • 描述
    兔多克隆抗体to CED6
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 235-265 of Human CED6

  • 阳性对照
    • CEM cell lysate, Human skeletal muscle tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明This antibody is purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab103642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 34 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
  • 组织特异性Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
  • 序列相似性Belongs to the ced-6 family.
    Contains 1 PID domain.
  • 细胞定位Cytoplasm. May associate with the cytoplasmic side of the plasma membrane and early endosomes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CED6 antibody
    • Cell death protein 6 homolog antibody
    • Engulfment adapter protein antibody
    • Engulfment adaptor PTB domain containing 1 antibody
    • GULP antibody
    • GULP, engulfment adaptor PTB domain containing 1 antibody
    • GULP1 antibody
    • GULP1_HUMAN antibody
    • Protein GULP antibody
    • PTB domain adapter protein CED 6 antibody
    • PTB domain adapter protein CED-6 antibody
    • PTB domain adaptor protein CED6 antibody
    • PTB domain-containing engulfment adapter protein 1 antibody
    see all

Anti-CED6 antibody 图像

  • Anti-CED6 antibody (ab103642) at 1/100 dilution + CEM cell lysate at 35 µg

    Predicted band size : 34 kDa
  • IHC analysis in formalin fixed and paraffin embedded Human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining, using ab103642 at a dilution of 1/50.

Anti-CED6 antibody (ab103642)参考文献

ab103642 has not yet been referenced specifically in any publications.

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