概述

  • 产品名称Anti-CEBP Beta抗体
    参阅全部 CEBP Beta 一抗
  • 描述
    兔多克隆抗体to CEBP Beta
  • 特异性ab53138 detects endogenous levels of total CEBP Beta protein.
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A synthetic non-phosphopeptide derived from human CEBP Beta around the phosphorylation site of threonine 235 (P-G-T-P-S).

  • 阳性对照
    • NIH/3T3 cell extracts and human lung carcinoma tissue.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab53138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/300 - 1/1000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).
IHC-P Use at an assay dependent concentration.
ELISA 1/10000.

靶标

  • 功能Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation.
  • 组织特异性Expressed at low levels in the lung, kidney and spleen.
  • 序列相似性Belongs to the bZIP family. C/EBP subfamily.
    Contains 1 bZIP domain.
  • 结构域the 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
  • 翻译后修饰Sumoylated by polymeric chains of SUMO2 or SUMO3.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AGP/EBP antibody
    • C EBP beta antibody
    • C/EBP beta antibody
    • C/EBP related protein 2 antibody
    • CCAAT Enhancer Binding Protein beta antibody
    • CCAAT/enhancer-binding protein beta antibody
    • CEBPB antibody
    • CEBPB_HUMAN antibody
    • CRP2 antibody
    • IL 6DBP antibody
    • IL6DBP antibody
    • Interleukin 6 dependent binding protein antibody
    • LAP antibody
    • Liver activator protein antibody
    • Liver enriched transcriptional activator antibody
    • NF IL6 antibody
    • NFIL6 antibody
    • Nuclear factor NF IL6 antibody
    • Nuclear factor NF-IL6 antibody
    • SF B antibody
    • SFB antibody
    • Silencer factor B antibody
    • TCF-5 antibody
    • TCF5 antibody
    • Transcription factor 5 antibody
    see all

Anti-CEBP Beta antibody 图像

  • All lanes : Anti-CEBP Beta antibody (ab53138) at 1/300 dilution

    Lane 1 : NIH/3T3 cell extract
    Lane 2 : NIH/3T3 cell extract with immunizing peptide


    Predicted band size : 36 kDa
    Observed band size : 36 kDa
  • ab53138 at 1/50 dilution staining CEBP Beta in human lung carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

Anti-CEBP Beta antibody (ab53138)参考文献

This product has been referenced in:
  • Mir RA & Chauhan SS Down Regulation of a Matrix Degrading Cysteine Protease Cathepsin L, by Acetaldehyde: Role of C/EBPa. PLoS One 6:e20768 (2011). WB ; Human . Read more (PubMed: 21687683) »
  • Younce CW  et al. MCP-1 (monocyte chemotactic protein-1)-induced protein, a recently identified zinc finger protein, induces adipogenesis in 3T3-L1 pre-adipocytes without peroxisome proliferator-activated receptor gamma. J Biol Chem 284:27620-8 (2009). WB ; Mouse . Read more (PubMed: 19666473) »

See all 2 Publications for this product

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