Anti-CEBP Alpha/CEBPA抗体[15C8] (ab15047)
Key features and details
- Mouse monoclonal [15C8] to CEBP Alpha/CEBPA
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-CEBP Alpha/CEBPA抗体[15C8]
参阅全部 CEBP Alpha/CEBPA 一抗 -
描述
小鼠单克隆抗体[15C8] to CEBP Alpha/CEBPA -
宿主
Mouse -
特异性
This antibody may cross react with glutamate--ammonia ligase domain containing 1 protein ((Lengsin) Lens glutamine synthase-like) as it has 8/10 aa identical to the immunogen used to generate ab15047 (this protein is part of the Glutamate synthetase family so its compartmentalization to the cytoplasm) unlike CEDPA which is found in the nucleus. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Hamster, Cow, Xenopus laevis, Schizosaccharomyces pombe, Zebrafish, Goldfish, Aspergillus nidulans, Neurospora crassa -
免疫原
Synthetic peptide corresponding to Mouse CEBP Alpha/CEBPA aa 1-14.
Sequence:MESADFYEVEPRPP
(Peptide available asab39791) -
表位
Amino terminal region. -
阳性对照
- Transfected hu293T cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.1% BSA -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
15C8 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab15047于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 2 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).
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说明 |
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WB
Use a concentration of 2 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa). |
靶标
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功能
C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. -
序列相似性
Belongs to the bZIP family. C/EBP subfamily.
Contains 1 bZIP domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 281677 Cow
- Entrez Gene: 1050 Human
- Entrez Gene: 140815 Zebrafish
- Omim: 116897 Human
- SwissProt: O02754 Cow
- SwissProt: P49715 Human
- Unigene: 76171 Human
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别名
- Apoptotic cysteine protease antibody
- Apoptotic protease Mch 5 antibody
- C/EBP alpha antibody
see all
图片
数据表及文件
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Datasheet download
文献 (4)
ab15047 被引用在 4 文献中.
- You L et al. Extract of Acalypha australis L. inhibits lipid accumulation and ameliorates HFD-induced obesity in mice through regulating adipose differentiation by decreasing PPAR? and CEBP/a expression. Food Nutr Res 65:N/A (2021). PubMed: 33776618
- Xu Q et al. All-trans retinoic acid controls differentiation, proliferation, and lipolysis in isolated subcutaneous adipocytes from peripartal Holstein cows. J Dairy Sci 104:4999-5008 (2021). PubMed: 33551168
- Meng X et al. Heterogeneous nuclear ribonucleoprotein A1 interacts with microRNA-34a to promote chondrogenic differentiation of mesenchymal stem cells. Am J Transl Res 9:1774-1782 (2017). WB ; Mouse . PubMed: 28469782
- Khanna-Gupta A et al. Up-regulation of Translation Eukaryotic Initiation Factor 4E in Nucleophosmin 1 Haploinsufficient Cells Results in Changes in CCAAT Enhancer-binding Protein a Activity: IMPLICATIONS IN MYELODYSPLASTIC SYNDROME AND ACUTE MYELOID LEUKEMIA. J Biol Chem 287:32728-37 (2012). WB . PubMed: 22851180