概述

  • 产品名称
    Anti-CEACAM3抗体
    参阅全部 CEACAM3 一抗
  • 描述
    兔多克隆抗体to CEACAM3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 55 and 241 of Human CEACAM3 (UniProt ID: P40198).

  • 阳性对照
    • A431 whole cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab111736 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 27 kDa.

靶标

  • 功能
    Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
  • 组织特异性
    CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney.
  • 序列相似性
    Belongs to the immunoglobulin superfamily. CEA family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 结构域
    The cytosolic domain is involved in S100A9 interaction.
  • 翻译后修饰
    Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • carcinoembryonic antibody
    • Carcinoembryonic antigen CGM1 antibody
    • Carcinoembryonic antigen gene family member 1 antibody
    • carcinoembryonic antigen related cell adhesion molecule 3 antibody
    • Carcinoembryonic antigen-related cell adhesion molecule 3 antibody
    • cd66 d antibody
    • CD66d antibody
    • CD66d antigen antibody
    • CEA antibody
    • CEACAM 3 antibody
    • CEACAM-3 antibody
    • Ceacam3 antibody
    • CEAM 3 antibody
    • CEAM-3 antibody
    • CEAM3 antibody
    • CEAM3_HUMAN antibody
    • CGM1 antibody
    • Nonspecific cross reacting antigen antibody
    • W264 antibody
    • W282 antibody
    see all

图片

  • Anti-CEACAM3 antibody (ab111736) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 27 kDa

实验方案

文献

ab111736 has not yet been referenced specifically in any publications.

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