概述

  • 产品名称Anti-CEACAM3抗体
    参阅全部 CEACAM3 一抗
  • 描述
    兔多克隆抗体to CEACAM3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within C-terminal amino acids 177-226 (AKTGRTSIQR DLKEQQPQAL APGRGPSHSS AFSMSPLSTA QAPLPNPRTA) of Human CEACAM3 (NP_001806).

  • 阳性对照
    • Human fetal liver lysate.

性能

应用

Our Abpromise guarantee covers the use of ab111510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
  • 组织特异性CGM1a, the predominant CGM1 transcript, is granulocyte-specific. Not detected out of the granulocytic lineage, such as monocytes, lymphocytes, spleen, testis, colon, brain, liver, pancreas, thymus, ovary, placenta, skeletal muscle, prostate, small intestine, heart, lung and kidney.
  • 序列相似性Belongs to the immunoglobulin superfamily. CEA family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • 结构域The cytosolic domain is involved in S100A9 interaction.
  • 翻译后修饰Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • carcinoembryonic antibody
    • Carcinoembryonic antigen CGM1 antibody
    • Carcinoembryonic antigen gene family member 1 antibody
    • carcinoembryonic antigen related cell adhesion molecule 3 antibody
    • Carcinoembryonic antigen-related cell adhesion molecule 3 antibody
    • cd66 d antibody
    • CD66d antibody
    • CD66d antigen antibody
    • CEA antibody
    • CEACAM 3 antibody
    • CEACAM-3 antibody
    • Ceacam3 antibody
    • CEAM 3 antibody
    • CEAM-3 antibody
    • CEAM3 antibody
    • CEAM3_HUMAN antibody
    • CGM1 antibody
    • Nonspecific cross reacting antigen antibody
    • W264 antibody
    • W282 antibody
    see all

Anti-CEACAM3 antibody 图像

  • Anti-CEACAM3 antibody (ab111510) at 1 µg/ml + Human fetal liver lysate at 10 µg

    Predicted band size : 27 kDa

Anti-CEACAM3 antibody (ab111510)参考文献

ab111510 has not yet been referenced specifically in any publications.

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