Anti-CEACAM1抗体[GM8G5] (ab26279)
Key features and details
- Mouse monoclonal [GM8G5] to CEACAM1
- Suitable for: IHC-Fr
- Reacts with: Human
- Isotype: IgG1
概述
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产品名称
Anti-CEACAM1抗体[GM8G5]
参阅全部 CEACAM1 一抗 -
描述
小鼠单克隆抗体[GM8G5] to CEACAM1 -
宿主
Mouse -
特异性
ab26279 recognises CEACAM1 transiently expressed on the cell surface of transfected BOSC cells as well as the naturally expressed protein. As the A2 domain is unique to CEACAM1, ab26279 can be used to distinguish CEACAM1 from all other CEACAM. -
经测试应用
适用于: IHC-Frmore details -
种属反应性
与反应: Human -
免疫原
Human CEACAM1-A2 domain cDNA (see relevance text).
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常规说明
ab26279 was generated by genetic immunisation of BALB/c mice with an immunisation vector containing the cDNA of the human CEACAM1-A2 domain.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
Primary antibody说明
ab26279 was generated by genetic immunisation of BALB/c mice with an immunisation vector containing the cDNA of the human CEACAM1-A2 domain. -
克隆
单克隆 -
克隆编号
GM8G5 -
同种型
IgG1 -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab26279于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-Fr |
Use at an assay dependent concentration.
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说明 |
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IHC-Fr
Use at an assay dependent concentration. |
靶标
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序列相似性
Belongs to the immunoglobulin superfamily. CEA family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Secreted; Cell membrane and Cell membrane. Localizes to sites of cell-cell contact. - Information by UniProt
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数据库链接
- Entrez Gene: 634 Human
- Omim: 109770 Human
- SwissProt: P13688 Human
- Unigene: 512682 Human
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形式
There are 11 isoforms produced by alternative splicing. Isoform 1 = BGPa; CEACAM1-4L; TM1-CEA; Isoform 2 = BGPg; CEACAM1-4C1; Isoform 3 = BGPh; CEACAM1-3; Isoform 4 = BGPi; CEACAM1-3C2; Isoform 5 = BGPy; CEACAM1-3AL; Isoform 6 = BGPb; CEACAM1-3L; TM2-CEA; Isoform 7 = BGPx; CEACAM1-1L; Isoform 8 = BGPc; CEACAM1-4S; TM3-CEA; Isoform 9 = BGPz; CEACAM1-3AS and Isoform 11 = BGPd; CEACAM1-3S. -
别名
- Antigen CD66 antibody
- BGP 1 antibody
- BGP antibody
see all
图片
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Immunohistological staining of colon tissue with ab26279. Cryosections of colon tissue were stained with 10 ug/ml ab26279 diluted in PBS containing 2.5% horse serum (B). PBS 2.5% horse serum served as negative control (A). Arrows indicate representative sections of analysed tissues. Detection of ab26279 occurred with a biotinylated anti-mouse-IgG secondary antibody and a streptavidin-peroxidase conjugate. Diaminobenzidine was used as substrate. Nuclei were stained with hematoxilin.
数据表及文件
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Datasheet download
文献 (3)
ab26279 被引用在 3 文献中.
- Goldson TM et al. Nucleolin mediates the binding of cancer cells to L-selectin under conditions of lymphodynamic shear stress. Am J Physiol Cell Physiol 318:C83-C93 (2020). PubMed: 31644306
- Thomas SN et al. Carcinoembryonic Antigen and CD44 Variant Isoforms Cooperate to Mediate Colon Carcinoma Cell Adhesion to E- and L-selectin in Shear Flow. J Biol Chem 283:15647-55 (2008). Flow Cyt ; Human . PubMed: 18375392
- Beaslas O et al. TRANSCRIPTOME RESPONSE OF ENTEROCYTES TO DIETARY LIPIDS: IMPACT ON CELL ARCHITECTURE, SIGNALING AND METABOLISM GENES. Am J Physiol Gastrointest Liver Physiol : (2008). PubMed: 18755805