Anti-CDX2抗体[CDX2-88], prediluted (ab86949)


  • 产品名称Anti-CDX2抗体[CDX2-88], prediluted
    参阅全部 CDX2 一抗
  • 描述
    小鼠单克隆抗体[CDX2-88] to CDX2, prediluted
  • 经测试应用适用于: IHC-P, Flow Cytmore details
  • 种属反应性
    与反应: Rat, Dog, Human
  • 免疫原

    CDX2 protein (Human)

  • 阳性对照
    • Colon cancer Normal Tissue: Colon Abnormal Tissue: Colon cancer, cyst adenocarcinoma and mucinous ovarian cancer



Our Abpromise guarantee covers the use of ab86949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Primary Antibody: incubate for 30 minutes at RT.
Flow Cyt Use at an assay dependent concentration. Use Neat

ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • 功能Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
  • 序列相似性Belongs to the Caudal homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 翻译后修饰Phosphorylation of Ser-60 mediates the transactivation capacity.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Caudal type homeo box 2 antibody
    • Caudal type homeo box transcription factor 2 antibody
    • Caudal type homeobox 2 antibody
    • Caudal type homeobox protein 2 antibody
    • Caudal type homeobox transcription factor 2 antibody
    • Caudal-type homeobox protein 2 antibody
    • CDX 2 antibody
    • CDX 3 antibody
    • CDX-3 antibody
    • Cdx2 antibody
    • CDX2_HUMAN antibody
    • CDX3 antibody
    • Homeobox protein CDX 2 antibody
    • Homeobox protein CDX-2 antibody
    see all

Anti-CDX2 antibody [CDX2-88], prediluted 图像

  • Prediluted ab86949, staining CDX2 in formalin fixed, paraffin embedded Human colon cancer tissue by Immunohistochemistry.
  • Overlay histogram showing HCT116 cells stained with ab86949 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab86949, neat) for 30 min at 22ºC. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed.

Anti-CDX2 antibody [CDX2-88], prediluted (ab86949)参考文献

This product has been referenced in:
  • Anani S  et al. Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo. Development 141:2813-24 (2014). Read more (PubMed: 24948601) »
  • Hashimoto K  et al. Immunohistochemical profile for unknown primary adenocarcinoma. PLoS One 7:e31181 (2012). IHC-P ; Human . Read more (PubMed: 22299055) »

See all 2 Publications for this product

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The flow data were obtained using 100ul neat antibody (undiluted) with 1x10^6 cells.

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