概述

  • 产品名称Anti-Cdk9抗体
    参阅全部 Cdk9 一抗
  • 描述
    小鼠单克隆抗体to Cdk9
  • 经测试应用适用于: Sandwich ELISA, WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Cow, Dog, Macaque Monkey
  • 免疫原

    GST-tagged recombinant fragment: QKRKVKDRLK AYVRDPYALD LIDKLLVLDP AQRIDSDDAL NHDFFWSDPM PSDLKGMLST HLTSMFEYLA PPRRKGSQIT QQSTNQSRNP ATTNQTEFER VF, corresponding to C terminal amino acids 271-372 of Human Cdk9 (AAH01968)

  • 阳性对照
    • Cdk9-transfected 293T cell lysate.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab76873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Sandwich ELISA Use a concentration of 5 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to Cdk9 (ab38840). For sandwich ELISA, use this antibody as Capture at 5 µg/ml with Rabbit polyclonal to Cdk9 (ab38840) as Detection.
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 43 kDa.
ELISA Use at an assay dependent dilution. Detection limit for recombinant tagged CDK9 is approximately 1ng/ml when used as a capture antibody.

靶标

  • 功能Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C-2K antibody
    • CDC2 related kinase antibody
    • CDC2L4 antibody
    • Cdk 9 antibody
    • Cdk9 antibody
    • CDK9_HUMAN antibody
    • Cell division cycle 2-like protein kinase 4 antibody
    • Cell division protein kinase 9 antibody
    • CTK1 antibody
    • Cyclin dependent kinase 9 antibody
    • Cyclin-dependent kinase 9 antibody
    • PITALRE antibody
    • Serine/threonine-protein kinase PITALRE antibody
    • TAK antibody
    • Tat associated kinase complex catalytic subunit antibody
    see all

Anti-Cdk9 antibody 图像

实验方案

Anti-Cdk9 antibody (ab76873)参考文献

ab76873 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab76873.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"