概述

  • 产品名称Anti-Cdk5抗体[8A1]
    参阅全部 Cdk5 一抗
  • 描述
    小鼠单克隆抗体[8A1] to Cdk5
  • 特异性ab28438 recognises Cyclin-dependentkinase-5 (CDK5).
  • 经测试应用适用于: ELISA, WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant full length protein (Human) His tagged recombinant human CDK5 protein purified from Baculovirus expressed insect cells

  • 阳性对照
    • SH-SY5Y cell lysates

性能

应用

Our Abpromise guarantee covers the use of ab28438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
IP
  • 应用说明ELISA: Use at an assay dependent dilution.
    IP: Use at a concentration of 2 µg/ml cell lysate.
    WB: 1/1000 - 1/2000. Detects a band of approximately 32 kDa (predicted molecular weight: 33 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.
    • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
      Contains 1 protein kinase domain.
    • 细胞定位Cytoplasm. Cell projection > lamellipodium. Cell projection > growth cone. In axonal growth cone with extension to the peripheral lamellipodia.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Cdk 5 antibody
      • Cdk5 antibody
      • CDK5_HUMAN antibody
      • Cell division protein kinase 5 antibody
      • Crk6 antibody
      • Cyclin dependent kinase 5 antibody
      • Cyclin-dependent kinase 5 antibody
      • Protein kinase CDK5 splicing antibody
      • PSSALRE antibody
      • Serine threonine protein kinase PSSALRE antibody
      • Serine/threonine-protein kinase PSSALRE antibody
      • Tau protein kinase II catalytic subunit antibody
      • TPKII catalytic subunit antibody
      see all

    Anti-Cdk5 antibody [8A1] 图像

    • All lanes : Anti-Cdk5 antibody [8A1] (ab28438) at 1/1000 dilution

      Lane 1 : SH-SY5Y cell lysates
      Lane 2 : SK-N-SH cell lysates
      Lane 3 : Mouse brain tissues


      Predicted band size : 33 kDa
      Observed band size : 32 kDa (why is the actual band size different from the predicted?)

    Anti-Cdk5 antibody [8A1] (ab28438)参考文献

    ab28438 has not yet been referenced specifically in any publications.

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